Davoudi: Lack of association between vitamin D insufficiency and clinical outcomes of patients with COVID-19 infection

Davoudi, 153 patient vitamin D sufficiency study: 12% higher mortality [p=1], 16% lower ventilation [p=1], 28% lower ICU admission [p=0.74], and 68% higher severe cases [p=0.3] https://c19p.org/davoudi

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Lack of association between vitamin D insufficiency and clinical outcomes of patients with COVID-19 infection

Davoudi et al., BMC Infectious Diseases, doi:10.1186/s12879-021-06168-7

18 May 2021 Source PDF Share Tweet

Retrospective 153 hospitalized patients in Iran, showing no significant difference in outcomes based on vitamin D levels. Adjusted results are only provided for vitamin D as a continuous variable.

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risk of death, 12.3% higher, RR 1.12, p = 1.00, high D levels (≥30ng/mL) 2 of 57 (3.5%), low D levels (<30ng/mL) 3 of 96 (3.1%).

risk of mechanical ventilation, 15.8% lower, RR 0.84, p = 1.00, high D levels (≥30ng/mL) 1 of 57 (1.8%), low D levels (<30ng/mL) 2 of 96 (2.1%), NNT 304.

risk of ICU admission, 27.8% lower, RR 0.72, p = 0.74, high D levels (≥30ng/mL) 3 of 57 (5.3%), low D levels (<30ng/mL) 7 of 96 (7.3%), NNT 49.

risk of severe case, 68.4% higher, RR 1.68, p = 0.30, high D levels (≥30ng/mL) 9 of 57 (15.8%), low D levels (<30ng/mL) 9 of 96 (9.4%).

Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates

This study is excluded in the after exclusion results of meta analysis: excessive unadjusted differences between groups.

Davoudi et al., 18 May 2021, retrospective, Iran, peer-reviewed, 11 authors, study period February 2020 - March 2020.

Contact: fkani63@gmail.com (corresponding author).

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