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0 0.5 1 1.5 2+ Symptomatic case 60% Improvement Relative Risk Symptomatic case (b) 58% c19vitamind.com Kalichuran et al. Vitamin D for COVID-19 Sufficiency Favors vitamin D Favors control
Kalichuran, 100 patient vitamin D sufficiency study: 60% fewer symptomatic cases [p<0.0001] https://c19p.org/kalichuran
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Vitamin D status and COVID-19 severity
Kalichuran et al., Southern African Journal of Infectious Diseases, doi:10.4102/sajid.v37i1.359
26 Apr 2022    Source   PDF   Share   Tweet
Prospective study of 100 COVID-19 patients in South Africa, 50 with COVID-19 pneumonia and 50 asymptomatic, showing higher risk of symptomatic COVID-19 with vitamin D deficiency and with lower exposure to sunlight.
Authors analyzed sunlight exposure in the previous week. It is not clear if this includes the time that patients could be symptomatic prior to going to the hospital. Symptomatic patients may be less likely to have sun exposure.
Sunlight exposure may be correlated with physical activity and can have additional benefits independent of vitamin D: [sciencedirect.com].
risk of symptomatic case, 60.0% lower, RR 0.40, p < 0.001, high D levels (≥20ng/mL) 56, low D levels (<20ng/mL) 44, inverted to make RR<1 favor high D levels (≥20ng/mL).
risk of symptomatic case, 58.2% lower, RR 0.42, p = 0.004, inverted to make RR<1 favor high D levels, higher sunlight exposure vs. lower sunlight exposure.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Kalichuran et al., 26 Apr 2022, prospective, South Africa, peer-reviewed, survey, 4 authors, study period September 2020 - February 2021.
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