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Vitamin D study #150   Meta Analysis
0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ ICU admission 44% Imp. Relative Risk, 95% CI Al-Salman: In COVID-19 patients, low 25-hydroxyvitamin D level in s.. c19vitamind.com/alsalman.html Favors vitamin D Favors control
7/29 Analysis of outcomes based on serum levels
Al-Salman et al., Nutrition & Food Science, doi:10.1108/NFS-05-2021-0143 (Peer Reviewed)
In COVID-19 patients, low 25-hydroxyvitamin D level in serum is associated with longer viral clearance time and higher risk of intensive care unit admission
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Retrospective 450 hospitalized patients in Bahrain, showing increased risk of ICU admission and slower viral clearance with vitamin D deficiency.
risk of ICU admission, 44.4% lower, RR 0.56, p = 0.03, high D levels (≥50nmol/L) 113, low D levels (<50nmol/L) 337, multinomial regression, RR approximated with OR.
Al-Salman et al., 7/29/2021, retrospective, Bahrain, Middle East, peer-reviewed, 5 authors.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical significance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.
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