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0 0.5 1 1.5 2+ Death/intubation -0% Improvement Relative Risk c19vitamind.com Walk et al. Vitamin D for COVID-19 Sufficiency Favors vitamin D Favors control
Walk, 133 patient vitamin D sufficiency study: no change in combined mortality/intubation [p=1] https://c19p.org/walk
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Vitamin D - contrary to vitamin K - does not associate with clinical outcome in hospitalized COVID-19 patients
Walk et al., medRxiv, doi:10.1101/2020.11.07.20227512 (Preprint)
9 Nov 2020    Source   PDF   Share   Tweet
Small retrospective study of 135 patients not finding a significant difference in vitamin D status. Patients with good outcomes had a median of 45.0 nmol/L versus 37.7 nmol/L for bad outcomes, p = 0.85.
Authors found that vitamin D sufficient persons had accelerated elastic fiber degradation, they hypothesize pro-calcification effects during COVID-19 and that vitamin K might compensate for this.
risk of death/intubation, 0.4% higher, RR 1.00, p = 1.00, high D levels 48 of 110 (43.6%), low D levels 10 of 23 (43.5%), >25nmol/L.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Walk et al., 11/9/2020, retrospective, Netherlands, Europe, preprint, 5 authors.
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