Vitamin D and Lung Outcomes in Elderly COVID-19 Patients

Vitamin D study #83 of 131 Meta Analysis

2/24 Pre-Exposure Prophylaxis study (treated before exposed to the virus)

Sulli et al., Nutrients, doi:10.3390/nu13030717 (Peer Reviewed)
Vitamin D and Lung Outcomes in Elderly COVID-19 Patients

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Retrospective 65 elderly COVID-19 patients and 65 matched controls, showing lower vitamin D levels associated with more severe lung involvement, longer disease duration, and higher mortality. Vitamin D supplementation was less common in the COVID-19 group compared to the control group.

Sulli et al., 2/24/2021, retrospective, Italy, Europe, peer-reviewed, 10 authors, dosage not specified.

risk of COVID-19 case, 50.4% lower, RR 0.50, p < 0.001, treatment 22 of 66 (33.3%), control 43 of 64 (67.2%), vitamin D supplementation.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.

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