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Home   COVID-19 treatment studies for Vitamin D  COVID-19 treatment studies for Vitamin D  C19 studies: Vitamin D  Vitamin D   Select treatmentSelect treatmentTreatmentsTreatments
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All Studies   Meta Analysis   Recent: 
0 0.5 1 1.5 2+ Mortality -192% Improvement Relative Risk ICU admission 39% Time to discharge 14% Recovery time 14% Recovery time (b) 21% c19vitamind.com Sabico et al. Vitamin D for COVID-19 RCT LATE TREATMENT Favors vitamin D Favors control
Sabico, 73 patient vitamin D late treatment RCT: 14% higher hospital discharge [p=0.14] and 14% faster recovery [p=0.97] https://c19p.org/sabico
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Effects of a 2-Week 5000 IU versus 1000 IU Vitamin D3 Supplementation on Recovery of Symptoms in Patients with Mild to Moderate Covid-19: A Randomized Clinical Trial
Sabico et al., Nutrients, doi:10.3390/nu13072170
24 Jun 2021    Source   PDF   Share   Tweet
Small RCT of 69 hospitalized patients comparing 1,000IU and 5,000IU daily cholecalciferol, showing faster recovery with the higher dose (statistically significant only for cough and ageusia).
risk of death, 192.1% higher, RR 2.92, p = 1.00, treatment 1 of 38 (2.6%), control 0 of 35 (0.0%), continuity correction due to zero event (with reciprocal of the contrasting arm).
risk of ICU admission, 38.9% lower, RR 0.61, p = 0.66, treatment 2 of 36 (5.6%), control 3 of 33 (9.1%), NNT 28.
time to discharge, 14.3% lower, relative time 0.86, p = 0.14, treatment 36, control 33.
recovery time, 14.1% lower, relative time 0.86, p = 0.97, treatment 36, control 33, fever.
recovery time, 20.5% lower, relative time 0.79, p = 0.24, treatment 36, control 33, dyspnea.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Sabico et al., 6/24/2021, Randomized Controlled Trial, Saudi Arabia, Middle East, peer-reviewed, 12 authors, study period 29 July, 2020 - 22 November, 2020.
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Late treatment
is less effective
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