Sabico, 73 patient vitamin D late treatment RCT: 14% higher hospital discharge [p=0.14] and 14% faster recovery [p=0.97] https://c19p.org/sabico
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Effects of a 2-Week 5000 IU versus 1000 IU Vitamin D3 Supplementation on Recovery of Symptoms in Patients with Mild to Moderate Covid-19: A Randomized Clinical Trial
et al., Nutrients, doi:10.3390/nu13072170
Small RCT of 69 hospitalized patients comparing 1,000IU and 5,000IU daily cholecalciferol, showing faster recovery with the higher dose (statistically significant only for cough and ageusia).
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risk of death, 192.1% higher, RR 2.92, p = 1.00, treatment 1 of 38 (2.6%), control 0 of 35 (0.0%), continuity correction due to zero event (with reciprocal of the contrasting arm).
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risk of ICU admission, 38.9% lower, RR 0.61, p = 0.66, treatment 2 of 36 (5.6%), control 3 of 33 (9.1%), NNT 28.
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time to discharge, 14.3% lower, relative time 0.86, p = 0.14, treatment 36, control 33.
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recovery time, 14.1% lower, relative time 0.86, p = 0.97, treatment 36, control 33, fever.
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recovery time, 20.5% lower, relative time 0.79, p = 0.24, treatment 36, control 33, dyspnea.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Sabico et al., 24 Jun 2021, Randomized Controlled Trial, Saudi Arabia, peer-reviewed, 12 authors, study period 29 July, 2020 - 22 November, 2020.
Late treatment
is less effective
is less effective
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