Reis, 214 patient vitamin D sufficiency study: 23% lower mortality [p=0.82], 45% higher ventilation [p=0.77], 33% higher hospital discharge [p=0.18], and 22% shorter hospitalization [p=0.06] https://c19p.org/reis4
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Influence of vitamin D status on hospital length of stay and prognosis in hospitalized patients with moderate to severe COVID-19: a multicenter prospective cohort study
et al., The American Journal of Clinical Nutrition, doi:10.1093/ajcn/nqab151
Prospective study of 220 hospitalized patients in Brazil, showing no significant differences based on vitamin D levels. There was a trend (p=0.057) towards longer hospital stay for patients with levels <10ng/mL.
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risk of death, 23.0% lower, HR 0.77, p = 0.82, high D levels (≥10ng/mL) 198, low D levels (<10ng/mL) 16, model 2, Cox proportional hazards.
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risk of mechanical ventilation, 45.0% higher, HR 1.45, p = 0.77, high D levels (≥10ng/mL) 198, low D levels (<10ng/mL) 16, adjusted per study, model 2, multivariable, Cox proportional hazards.
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risk of no hospital discharge, 33.3% lower, HR 0.67, p = 0.18, high D levels (≥10ng/mL) 198, low D levels (<10ng/mL) 16, adjusted per study, model 2, multivariable, Cox proportional hazards.
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hospitalization time, 22.2% lower, relative time 0.78, p = 0.06, high D levels (≥10ng/mL) 191, low D levels (<10ng/mL) 15, model 2.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Reis et al., 5/21/2021, prospective, Brazil, South America, peer-reviewed, 19 authors.
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