Rastogi, 40 patient vitamin D late treatment RCT: 53% improved viral clearance [p=0.02] https://c19p.org/rastogi
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Short term, high-dose vitamin D supplementation for COVID-19 disease: a randomised, placebo-controlled, study (SHADE study)
et al., Postgraduate Medical Journal, doi:10.1136/postgradmedj-2020-139065
53% reduction in PCR+ with high-dose cholecalciferol supplementation. RCT with 16 treatment patients and 24 control patients. 25(OH)D levels at day 14 were 52 ng/ml vs. 15 ng/ml in the intervention and control group.
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risk of no viral clearance, 52.6% lower, RR 0.47, p = 0.02, treatment 6 of 16 (37.5%), control 19 of 24 (79.2%), NNT 2.4.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Rastogi et al., 12 Nov 2020, Randomized Controlled Trial, India, peer-reviewed, 8 authors, dosage 60,000IU days 1-7.
Late treatment
is less effective
is less effective
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