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All Studies   Meta Analysis   Recent: 
Discovery of re-purposed drugs that slow SARS-CoV-2 replication in human cells
Pickard et al., PLOS Pathogens, doi:10.1371/journal.ppat.1009840 (In Vitro)
9 Sep 2021    Source   PDF   Share   Tweet
In Vitro studying identifying 35 compounds that inhibit SARS-CoV-2 in Vero cells and hepatocytes when treated prior to infection, and several compounds that slow replication when treated after infection: vitamin D, amodiaquine, atovaquone, bedaquiline, ebastine, LY2835219, manidipine, and panobinosta. Authors use a nano-luciferase tagged version of the virus to quantify viral load.
Pickard et al., 9/9/2021, peer-reviewed, 7 authors.
In Vitro studies are an important part of preclinical research, however results may be very different in vivo.
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