Nguyen, vitamin D sufficiency study: 81% lower mortality [p=0.008], 53% lower ventilation [p=0.13], and 74% higher hospital discharge [p<0.0001] https://c19p.org/nguyen3
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25-hydroxyvitamin D is a predictor of COVID-19 severity of hospitalized patients
et al., PLOS ONE, doi:10.1371/journal.pone.0268038
Retrospective 88 COVID-19 hospitalized patients and 122 controls, showing higher mortality, ventilation, and length of stay with vitamin D deficiency.
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risk of death, 81.1% lower, OR 0.19, p = 0.008, cutoff 20ng/mL, adjusted per study, inverted to make OR<1 favor high D levels (≥20ng/mL), 25-OH-D3, multivariable, RR approximated with OR.
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risk of mechanical ventilation, 52.8% lower, OR 0.47, p = 0.13, cutoff 20ng/mL, adjusted per study, inverted to make OR<1 favor high D levels (≥20ng/mL), 25-OH-D3, multivariable, RR approximated with OR.
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risk of no hospital discharge, 74.0% lower, HR 0.26, p < 0.001, cutoff 20ng/mL, 25-OH-D3, Cox proportional hazards.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Nguyen et al., 3 May 2022, retrospective, USA, peer-reviewed, 11 authors, study period 15 July, 2020 - 15 October, 2020.
Contact:
nguyen.nguyen2@bswhealth.org.
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