Association of Vitamin D Status and Other Clinical Characteristics With COVID-19 Test Results

9/3 Analysis of outcomes based on serum levels

Meltzer et al., JAMA network open, 3:9, doi:10.1001/jamanetworkopen.2020.19722 (Peer Reviewed)
Association of Vitamin D Status and Other Clinical Characteristics With COVID-19 Test Results

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Retrospective 489 patients showing 44% lower risk for COVID-19 with vitamin D sufficiency, relative risk RR = 0.56, p = 0.02.

Meltzer et al., 9/3/2020, retrospective, USA, North America, peer-reviewed, 6 authors.

risk of COVID-19 case, 43.5% lower, RR 0.56, p = 0.02, high D levels 39 of 317 (12.3%), low D levels 32 of 172 (18.6%), adjusted per study, >20ng/mL.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.

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