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All Studies   Meta Analysis   Recent: 
0 0.5 1 1.5 2+ Mortality 9% Improvement Relative Risk Mortality (b) 30% late Mortality (c) 13% levels c19vitamind.com Mahmood et al. Vitamin D for COVID-19 Prophylaxis Favors vitamin D Favors control
Mahmood, 490 patient vitamin D prophylaxis study: 9% lower mortality [p=0.67] https://c19p.org/mahmood
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Coronavirus in HIP Fractures CHIP 2: Is Vitamin D Deficiency Associated with Increased Mortality from COVID-19 Infections in A Hip Fracture Population?
Mahmood et al., European Journal of Medical and Health Sciences, doi:10.24018/ejmed.2021.3.6.1159
29 Dec 2021    Source   PDF   Share   Tweet
Retrospective 517 hip fracture patients in the UK with vitamin D levels measured during COVID-19 admission, not showing significant differences in mortality for supplementation in unadjusted analysis with no group details and subject to confounding by indication. There was also no significant effect based on deficiency.
risk of death, 9.4% lower, RR 0.91, p = 0.67, treatment 34 of 138 (24.6%), control 31 of 114 (27.2%), NNT 39, prescribed by GP.
risk of death, 30.5% lower, RR 0.70, p = 0.10, treatment 45 of 238 (18.9%), control 31 of 114 (27.2%), NNT 12, started after admission, late treatment result.
risk of death, 12.5% lower, RR 0.87, p = 0.51, high D levels (≥25nmol/L) 70 of 346 (20.2%), low D levels (<25nmol/L) 40 of 144 (27.8%), adjusted per study, cutoff ≥25nmol/L, odds ratio converted to relative risk, outcome based on serum levels.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
This study is excluded in the after exclusion results of meta analysis: unadjusted results with no group details, substantial unadjusted confounding by indication likely.
Mahmood et al., 12/29/2021, retrospective, United Kingdom, Europe, peer-reviewed, 4 authors, study period 23 March, 2020 - 31 December, 2020, dosage varies.
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