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0 0.5 1 1.5 2+ Severe case 36% Improvement Relative Risk Hospitalization 29% Case 29% c19vitamind.com Li et al. Vitamin D for COVID-19 Sufficiency Favors vitamin D Favors control
Li, 353,299 patient vitamin D sufficiency study: 36% lower severe cases [p<0.0001], 29% lower hospitalization [p<0.0001], and 29% fewer cases [p<0.0001] https://c19p.org/li4
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Metabolic Healthy Obesity, Vitamin D Status, and Risk of COVID-19
Li et al., Aging and Disease, doi:10.14336/AD.2020.1108
11 Jan 2021    Source   PDF   Share   Tweet
UK Biobank retrospective 353,299 patients showing that vitamin D insufficiency and deficiency are associated with increased COVID-19 risk. This study also analyzes metabolic/obesity phenotypes and the combination with vitamin D status.
risk of severe case, 36.2% lower, RR 0.64, p < 0.001, NNT 932, odds ratio converted to relative risk, >25nmol/L.
risk of hospitalization, 28.8% lower, RR 0.71, p < 0.001, NNT 261, odds ratio converted to relative risk, >25nmol/L.
risk of case, 29.5% lower, RR 0.71, p < 0.001, NNT 823, odds ratio converted to relative risk, >25nmol/L.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Li et al., 1/11/2021, retrospective, population-based cohort, United Kingdom, Europe, peer-reviewed, 6 authors.
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