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Vitamin D study #168   Meta Analysis
0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Case 27% Imp. Relative Risk, 95% CI Lázaro: Vitamin D deficit in type 2 diabetes patients during COV.. c19vitamind.com/lazaro.html Favors vitamin D Favors control
9/5 Prophylaxis study
Lázaro et al., Endocrine Abstracts, doi:10.1530/endoabs.70.EP552 (Preprint)
Vitamin D deficit in type 2 diabetes patients during COVID-19 lockdown with and without supplementation
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Analysis of 239 consecutive diabetic patients, 97 taking vitamin D supplements, showing significantly higher vitamin D levels in supplemented patients. There was no statistically significant difference in cases based on supplementation, with only 3 cases total.
risk of case, 26.8% lower, RR 0.73, p = 1.00, treatment 1 of 97 (1.0%), control 2 of 142 (1.4%).
This study is excluded in the after exclusion results of meta analysis: very few events, unadjusted results with no group details, minimal details provided.
Lázaro et al., 9/5/2021, retrospective, Spain, Europe, preprint, 9 authors, dosage not specified.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical significance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.
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