Vitamin D Insufficiency is Prevalent in Severe COVID-19

4/28 Analysis of outcomes based on serum levels

Lau et al., medRxiv, doi:10.1101/2020.04.24.20075838 (Preprint)
Vitamin D Insufficiency is Prevalent in Severe COVID-19

Analysis of 20 hospitalized COVID-19 patients, 13 requiring ICU admission. 84.6% of the ICU patients had low vitamin D levels versus 57.1% of the non-ICU patients.

Lau et al., 4/28/2020, retrospective, USA, North America, preprint, 7 authors.

risk of ICU admission, 45.0% lower, RR 0.55, p = 0.29, high D levels 2 of 5 (40.0%), low D levels 11 of 15 (73.3%), >30ng/mL.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.

All 131 studies Meta Analysis

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