et al., Journal of Clinical Endocrinology & Metabolism, doi:10.1210/clinem/dgab439 (Peer Reviewed)
Retrospective 80,670 people in the UK with vitamin D levels measured within the last 12 months, showing higher risk of hospitalization with low vitamin D levels.
Jude et al., 6/17/2021, retrospective, United Kingdom, Europe, peer-reviewed, 5 authors.
risk of hospitalization, 71.6% lower, RR 0.28, p < 0.001, adjusted per study, odds ratio converted to relative risk, >25 nmol/L, control prevalence approximated with overall prevalence.
risk of hospitalization, 57.9% lower, RR 0.42, p < 0.001, adjusted per study, odds ratio converted to relative risk, >50 nmol/L, control prevalence approximated with overall prevalence.
Effect extraction follows pre-specified rules
prioritizing more serious outcomes. For an individual study the most serious
outcome may have a smaller number of events and lower statistical signficance,
however this provides the strongest evidence for the most serious outcomes
when combining the results of many trials.