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All Studies   Meta Analysis   Recent: 
0 0.5 1 1.5 2+ Mortality 94% Improvement Relative Risk Mortality (b) 58% c19vitamind.com Hafez et al. Vitamin D for COVID-19 LATE TREATMENT Favors vitamin D Favors control
Hafez, 42 patient vitamin D late treatment study: 94% lower mortality [p=0.07] https://c19p.org/hafez2
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Factors Influencing Disease Stability and Response to Tocilizumab Therapy in Severe COVID-19: A Retrospective Cohort Study
Hafez et al., Antibiotics, doi:10.3390/antibiotics11081078
9 Aug 2022    Source   PDF   Share   Tweet
Retrospective 49 severe COVID-19 patients treated with tocilizumab, showing lower mortality with vitamin D treatment and a dose-dependent response.
risk of death, 93.7% lower, RR 0.06, p = 0.07, treatment 0 of 7 (0.0%), control 12 of 30 (40.0%), NNT 2.5, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm), high dose, 50,000IU every other day for two weeks or one intramuscular shot of 300,000IU.
risk of death, 58.3% lower, RR 0.42, p = 0.28, treatment 2 of 12 (16.7%), control 12 of 30 (40.0%), NNT 4.3, low dose, ≤10,000IU/day.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Hafez et al., 9 Aug 2022, retrospective, Egypt, peer-reviewed, 2 authors, study period April 2020 - June 2020, dosage 50,000IU days 1, 3, 5, 7, 9, 11, 13, 50,000IU every other day for two weeks or one intramuscular shot of 300,000IU.
Contact: wael.hafez@nmc.ae (corresponding author).
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