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0 0.5 1 1.5 2+ Mortality 25% Improvement Relative Risk c19vitamind.com Güven et al. Vitamin D for COVID-19 ICU PATIENTS Favors vitamin D Favors control
Güven, 175 patient vitamin D ICU study: 25% lower mortality [p=0.32] https://c19p.org/guven
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The effect of high-dose parenteral vitamin D3 on COVID-19-related inhospital mortality in critical COVID-19 patients during intensive care unit admission: an observational cohort study
Güven et al, European Journal of Clinical Nutrition, doi:10.1038/s41430-021-00984-5
23 Jul 2021    Source   PDF   Share   Tweet
Retrospective 175 ICU patients, 113 treated with a single dose of 300,000IU intramuscular cholecalciferol, showing lower mortality with treatment, but not reaching statistical significance. Calcifediol or calcitriol, which avoids several days delay in conversion, may be more successful, especially with this very late stage usage.
risk of death, 24.8% lower, RR 0.75, p = 0.32, treatment 43 of 113 (38.1%), control 30 of 62 (48.4%), NNT 9.7, odds ratio converted to relative risk.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
This study is excluded in the after exclusion results of meta analysis: very late stage, ICU patients.
Güven et al., 7/23/2021, retrospective, Turkey, Europe, peer-reviewed, 2 authors, dosage 300,000IU single dose.
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