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Home   COVID-19 treatment studies for Vitamin D  COVID-19 treatment studies for Vitamin D  C19 studies: Vitamin D  Vitamin D   Select treatmentSelect treatmentTreatmentsTreatments
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0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Mortality 42% Improvement Relative Risk Mortality (b) 51% Severe case 38% Severe case (b) 35% c19vitamind.com/fatemi.html Favors vitamin D Favors control
30 November 2021 - Analysis of outcomes based on serum levels
Association of vitamin D deficiency with COVID-19 severity and mortality in Iranian people: a prospective observational study
Fatemi et al., Acute and Critical Care, doi:10.4266/acc.2021.00605 (Peer Reviewed)
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Prospective study of 248 hospitalized COVID+ patients in Iran with vitamin D levels measured in the previous year and again at admission, showing vitamin D status associated with severity and mortality.
risk of death, 42.0% lower, RR 0.58, p = 0.07, high D levels 18 of 139 (12.9%), low D levels 25 of 109 (22.9%), NNT 10, odds ratio converted to relative risk, vitamin D measured prior to COVID-19, multivariate.
risk of death, 51.1% lower, RR 0.49, p = 0.02, high D levels 13 of 115 (11.3%), low D levels 30 of 133 (22.6%), NNT 8.9, odds ratio converted to relative risk, vitamin D measured on admission, multivariate.
risk of severe case, 37.9% lower, RR 0.62, p = 0.007, high D levels 38 of 139 (27.3%), low D levels 48 of 109 (44.0%), NNT 6.0, vitamin D measured prior to COVID-19.
risk of severe case, 34.8% lower, RR 0.65, p = 0.02, high D levels 31 of 115 (27.0%), low D levels 55 of 133 (41.4%), NNT 6.9, vitamin D measured on admission.
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
Fatemi et al., 11/30/2021, prospective, Iran, Middle East, peer-reviewed, 5 authors, study period 1 October, 2020 - 31 May, 2021.
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