COVID-19 in Parkinson’s Disease Patients Living in Lombardy, Italy

Vitamin D study #113 of 131 Meta Analysis

6/2 Pre-Exposure Prophylaxis study (treated before exposed to the virus)

Fasano et al., Movement Disorders, doi:10.1002/mds.28176 (Peer Reviewed)
COVID-19 in Parkinson’s Disease Patients Living in Lombardy, Italy

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Retrospective phone survey of 1,486 Parkinson's disease patients in Italy, showing lower risk of COVID-19 cases with vitamin D supplementation. This paper also presents a case control study of PD patients and family member control patients.

Fasano et al., 6/2/2021, retrospective, Italy, Europe, peer-reviewed, 7 authors, dosage not specified.

risk of COVID-19 case, 42.0% lower, RR 0.58, p = 0.05, treatment 13 of 329 (4.0%), control 92 of 1157 (8.0%), odds ratio converted to relative risk.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.

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