12 August 2021 - Analysis of outcomes based on serum levels
Vitamin D levels associate with blood glucose and BMI in COVID-19 patients predicting disease severity
et al, The Journal of Clinical Endocrinology & Metabolism, doi:10.1210/clinem/dgab599
(Peer Reviewed)
Retrospective 88 patients in Italy, showing vitamin D deficiency associated with severe cases, blood glucose, and BMI.
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risk of death, 10.7% lower, RR 0.89, p = 1.00, high D levels 5 of 28 (17.9%), low D levels 12 of 60 (20.0%), NNT 47, >20ng/mL.
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risk of ICU admission, 41.6% lower, RR 0.58, p = 0.22, high D levels 6 of 28 (21.4%), low D levels 22 of 60 (36.7%), NNT 6.6, >20ng/mL.
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risk of severe case, 39.6% lower, RR 0.60, p = 0.04, high D levels 11 of 28 (39.3%), low D levels 39 of 60 (65.0%), NNT 3.9, >20ng/mL.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. |
di Filippo et al., 8/12/2021, retrospective, Italy, Europe, peer-reviewed, 8 authors.
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