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0 0.5 1 1.5 2+ Mortality 11% Improvement Relative Risk ICU admission 42% Severe case 40% c19vitamind.com di Filippo et al. Vitamin D for COVID-19 Sufficiency Favors vitamin D Favors control
di Filippo, 88 patient vitamin D sufficiency study: 11% lower mortality [p=1], 42% lower ICU admission [p=0.22], and 40% lower severe cases [p=0.04] https://c19p.org/difilippo
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Vitamin D levels associate with blood glucose and BMI in COVID-19 patients predicting disease severity
di Filippo et al, The Journal of Clinical Endocrinology & Metabolism, doi:10.1210/clinem/dgab599
12 Aug 2021    Source   PDF   Share   Tweet
Retrospective 88 patients in Italy, showing vitamin D deficiency associated with severe cases, blood glucose, and BMI.
risk of death, 10.7% lower, RR 0.89, p = 1.00, high D levels 5 of 28 (17.9%), low D levels 12 of 60 (20.0%), NNT 47, >20ng/mL.
risk of ICU admission, 41.6% lower, RR 0.58, p = 0.22, high D levels 6 of 28 (21.4%), low D levels 22 of 60 (36.7%), NNT 6.6, >20ng/mL.
risk of severe case, 39.6% lower, RR 0.60, p = 0.04, high D levels 11 of 28 (39.3%), low D levels 39 of 60 (65.0%), NNT 3.9, >20ng/mL.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
di Filippo et al., 8/12/2021, retrospective, Italy, Europe, peer-reviewed, 8 authors.
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