Demir, 210 patient vitamin D sufficiency study: 89% lower severe cases [p=0.001], 87% shorter hospitalization [p=0.001], and 24% fewer cases [p=0.18] https://c19p.org/demir
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Vitamin D deficiency is associated with COVID‐19 positivity and the severity of the disease
et al., Journal of Medical Virology, doi:10.1002/jmv.26832
Retrospective cohort study of 487 patients finding that lower vitamin D levels is associated with more severe cases as measured by affected lung segments and increased hospitalization time for COVID-19 positive patients, and that lower vitamin D levels increases COVID-19 PCR+ cases.
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risk of severe case, 89.3% lower, RR 0.11, p < 0.001, high D levels 13, low D levels 99, ratio of the mean number of affected lung segments, >30ng/ml vs. <=10ng/mL.
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hospitalization time, 87.1% lower, relative time 0.13, p < 0.001, high D levels 13, low D levels 99, >30ng/ml vs. <=10ng/mL.
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risk of case, 24.2% lower, RR 0.76, p = 0.18, high D levels 13 of 31 (41.9%), low D levels 99 of 179 (55.3%), NNT 7.5, >30ng/ml vs. <=10ng/mL.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Demir et al., 1/29/2021, retrospective, Turkey, Europe, peer-reviewed, 3 authors.
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