Charoenngam, 287 patient vitamin D sufficiency study: 34% lower mortality [p=0.26], 37% lower ventilation [p=0.17], and 23% lower ICU admission [p=0.28] https://c19p.org/charoenngam
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Association of vitamin D status with hospital morbidity and mortality in adult hospitalized COVID-19 patients
et al., Endocrine Practice, doi:10.1016/j.eprac.2021.02.013
Retrospective 287 hospitalized patients in the USA showing significantly lower mortality with vitamin D sufficiency in elderly patients and patients without obesity; and lower mortality for all patients but not reaching statistical signifance.
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risk of death, 34.1% lower, RR 0.66, p = 0.26, high D levels 12 of 100 (12.0%), low D levels 29 of 187 (15.5%), adjusted per study, odds ratio converted to relative risk, >=30ng/mL.
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risk of mechanical ventilation, 37.2% lower, RR 0.63, p = 0.17, high D levels 14 of 100 (14.0%), low D levels 34 of 187 (18.2%), adjusted per study, odds ratio converted to relative risk, >=30ng/mL.
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risk of ICU admission, 23.1% lower, RR 0.77, p = 0.28, high D levels 25 of 100 (25.0%), low D levels 56 of 187 (29.9%), NNT 20, adjusted per study, odds ratio converted to relative risk, >=30ng/mL.
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risk of death, 58.1% lower, RR 0.42, p = 0.05, high D levels 7 of 57 (12.3%), low D levels 25 of 79 (31.6%), NNT 5.2, adjusted per study, odds ratio converted to relative risk, >65 years old, >=30ng/mL.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Charoenngam et al., 3/8/2021, retrospective, USA, North America, peer-reviewed, 6 authors.
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