Cereda, 197 patient vitamin D prophylaxis study: 73% higher mortality [p=0.14] and 17% higher hospitalization [p=0.68] https://c19p.org/cereda2
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Vitamin D supplementation and outcomes in coronavirus disease 2019 (COVID-19) patients from the outbreak area of Lombardy, Italy
et al., Nutrition, doi:10.1016/j.nut.2020.111055
Retrospective 105 Parkinson's disease patients, 92 caregivers, and 127 hospital inpatients, showing higher, but not statistically significant mortality and hospitalization with treatment. Supplementation was defined as >=25,000IU/month for at least 3 months.
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risk of death, 73.0% higher, RR 1.73, p = 0.14, treatment 7 of 18 (38.9%), control 40 of 152 (26.3%), odds ratio converted to relative risk, >=25,000IU/month for at least 3 months.
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risk of hospitalization, 17.3% higher, RR 1.17, p = 0.68, treatment 7 of 27 (25.9%), control 36 of 170 (21.2%), odds ratio converted to relative risk.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Cereda et al., 11/11/2020, retrospective, Italy, Europe, peer-reviewed, mean age 68.8, 7 authors, dosage varies.
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