Baykal, 75 patient vitamin D late treatment study: 22% lower mortality [p=0.43] and 59% lower ICU admission [p=0.005] https://c19p.org/baykal
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Correlation of vitamin D level with the clinical-radiological severity of COVID-19 in geriatric patients
et al., Journal of Health Sciences and Medicine, doi:10.32322/jhsm.1063405
Retrospective 75 patients in Turkey showing lower ICU admission with vitamin D treatment in unadjusted results subject to confounding by time and indication (treatment was given to patients with low levels and only during a certain period). There was no significant difference in outcomes based on vitamin D levels.
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risk of death, 22.2% lower, RR 0.78, p = 0.43, treatment 7 of 18 (38.9%), control 28 of 56 (50.0%), NNT 9.0, excluded in exclusion analyses:
unadjusted results with no group details, significant confounding by time possible due to separation of groups in different time periods.
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risk of ICU admission, 59.4% lower, RR 0.41, p = 0.005, treatment 5 of 18 (27.8%), control 39 of 57 (68.4%), NNT 2.5, excluded in exclusion analyses:
unadjusted results with no group details, significant confounding by time possible due to separation of groups in different time periods.
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risk of death, 8.0% higher, RR 1.08, p = 0.80, high D levels (≥20ng/mL) 11 of 20 (55.0%), low D levels (<20ng/mL) 28 of 55 (50.9%), cutoff ≥20ng/mL, outcome based on serum levels.
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risk of ICU admission, 4.8% lower, RR 0.95, p = 1.00, high D levels (≥20ng/mL) 9 of 20 (45.0%), low D levels (<20ng/mL) 26 of 55 (47.3%), NNT 44, cutoff ≥20ng/mL, outcome based on serum levels.
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risk of progression, 6.1% lower, RR 0.94, p = 0.77, high D levels (≥20ng/mL) 14 of 20 (70.0%), low D levels (<20ng/mL) 41 of 55 (74.5%), NNT 22, cutoff ≥20ng/mL, severe/critical, outcome based on serum levels.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Baykal et al., 5/30/2022, retrospective, Turkey, peer-reviewed, 2 authors, study period 1 April, 2020 - 1 March, 2021, dosage 300,000IU single dose.
Contact:
drhusnubaykal@hotmail.com.
Late treatment
is less effective
is less effective
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