Vitamin D status and outcomes for hospitalised older patients with COVID-19

Vitamin D study #21 of 131 Meta Analysis

8/27 Analysis of outcomes based on serum levels

Baktash et al., Postgraduate Medical Journal, doi:10.1136/postgradmedj-2020-138712 (Peer Reviewed)
Vitamin D status and outcomes for hospitalised older patients with COVID-19

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Prospective study of 105 hospitalized patients, showing lower vitamin D levels in the COVID-19 positive group (27.0 nmol/L vs 52.0 nmol/L, p=0.0008), and non-statistically significant higher mortality with vitamin D deficiency.

Baktash et al., 8/27/2020, prospective, United Kingdom, Europe, peer-reviewed, 8 authors.

risk of death, 28.6% lower, RR 0.71, p = 0.50, high D levels 4 of 31 (12.9%), low D levels 6 of 39 (15.4%), adjusted per study, >30nmol/L.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.

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