Retrospective 144 patients in the USA showing significantly lower mortality for vitamin D levels >=30ng/mL.
Angelidi et al., 1/9/2021, retrospective, USA, North America, peer-reviewed, 8 authors.
risk of death, 88.0% lower, RR 0.12, p = 0.01, high D levels 6 of 65 (9.2%), low D levels 20 of 79 (25.3%), adjusted per study, >30ng/mL, supplementary table 2, multivariable logistic regression model 5.
Effect extraction follows pre-specified rules prioritizing more serious
outcomes. For an individual study the most serious outcome may have a smaller
number of events and lower statistical signficance, however this provides the
strongest evidence for the most serious outcomes when combining the results of
many trials.