Possible association of vitamin D status with lung involvement and outcome in patients with COVID-19: a retrospective study

Vitamin D study #37 of 131 Meta Analysis

10/30 Analysis of outcomes based on serum levels

Abrishami et al., European Journal of Nutrition, doi:10.1007/s00394-020-02411-0 (Peer Reviewed)
Possible association of vitamin D status with lung involvement and outcome in patients with COVID-19: a retrospective study

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Retrospective 73 hospitalized patients showing the probability of death in patients with vitamin D deficiency (< 25ng/mL) was 34.6% compared with 6.4% in patients with sufficient vitamin D levels.

Abrishami et al., 10/30/2020, retrospective, Iran, Middle East, peer-reviewed, mean age 55.2, 7 authors.

risk of death, 75.9% lower, RR 0.24, p = 0.04, high D levels 3 of 47 (6.4%), low D levels 9 of 26 (34.6%), adjusted per study, >25ng/mL.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.

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